Lundberg FE, et al. - Through a population-based cohort study involving 2,863,585 men born 1944–1992 in Sweden, researchers investigated mortality in men with infertility (failure to accomplish a clinical pregnancy following ≥ 12 months of regular unprotected sexual intercourse) or infertility-related diagnosis. Corresponding to a crude incidence rate of 1.56 deaths per 1,000 person-years, 439 men with a diagnosis of infertility died during follow-up. These figures can be compared with 1,400 and 99,463 deaths in men with an infertility-related diagnosis and in reference individuals, respectively. Overall, infertile men did not have a higher risk of death; they did, however, have a higher risk of death prior to the age of 30 (20–29 years). This early excess mortality was extensively described by cancer diagnosed prior to infertility. Having an infertility-related diagnosis had a correlation with death. The lack of general screening for infertility in Sweden and the lack of knowledge on semen parameters were limitations of this study. Therefore, men with a diagnosis of infertility were not found to be at a higher risk of death vs general population; however, having a diagnosis associated with infertility may be correlated to a higher risk of death.