Lum ZC, et al. - Researchers performed a systematic review to evaluate the mortality rate of a periprosthetic joint infection of the knee undergoing two stage revision for infection. They assessed if this rate improved over time and how was this different from a normal cohort of individuals. After two-stage total knee revision, the mortality rate for infection is very high. Experts suggested discussing death while counseling a patient regarding complications of this disease. After total knee PJI, the one-year mortality rate was 4.33% with an increase of 3.13% per year mortality thereafter.