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Mortality among solid organ waitlist candidates during COVID‐19 in the United States

American Journal of Transplantation Mar 01, 2021

Miller J, Wey A, Musgrave D, et al. - Researchers here investigated how COVID‐19 affected solid organ waiting list mortality in the United States and compared the effects across patient demographics (eg, race, age, gender) and donation service areas. The overall, demographic‐specific, and donation service area‐specific differences in the hazard of waitlist mortality before and after the national emergency declaration on March 13, 2020, were determined for each solid organ using three separate piecewise exponential survival models. They observed higher kidney waiting list mortality after than before the national emergency. For liver, pancreas, lung, and heart, there was no significant difference in the hazard of waitlist mortality before and after COVID‐19. Across donation service areas, kidney candidates had notable variability in disparities. Increased waiting list mortality was observed in only Blacks vs Whites for kidney candidates. Findings thereby suggest heterogeneous effects of the first 10 weeks after the declaration of a national emergency on the waitlist mortality rate, that varied by geography and ethnicity.

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