Lunyera J, et al. – In this study, researchers investigated the links between plasma 25(OH)D and the annual rate of estimated glomerular filtration rate (eGFR) decline as well as incident CKD in a cohort of black Americans. Overall, 25(OH)D was not linked to the decline in eGFR in fully-adjusted models. However, higher 25(OH)D correlated with slower eGFR decline among those with diabetes: each 5 ng/ml higher 25(OH)D related to 0.55 ml/min/1.73m²/year slower eGFR decline. Similarly, higher 25(OH)D was not generally associated with the CKD incident but was associated with lower odds of the CKD incident among participants with the GG or GT genotype at rs7041 in the gene encoding vitamin D binding protein (DBP). These findings supported the premise of a potentially higher 25(OH)D benefit for kidney health in black Americans with diabetes or specific variants of DBP.