Liu H, Tian Y, Luo G, et al. - In benign prostate hyperplasia (BPH) patients, the clinical symptoms and surgical efficacy can be predicted to a certain extent by both modified bladder outlet obstruction index (MBOOI) and bladder outlet obstruction index (BOOI), but MBOOI, in comparison to BOOI, affords a likely more useful factor that can aid the prediction of the surgical efficacy of transurethral resection of the prostate (TURP).

• A total of 403 patients with BPH were analyzed to determine the clinical value of the MBOOI and its use in predicting surgical efficacy in men undergoing TURP.

• Estimation of BOOI and MBOOI was done, and surgical efficacy was determined by the improvements in International Prostate Symptom Score (IPSS), quality of life (QoL), and Q _max 6 months post-surgery.

• On comparing effective and ineffective groups depending on the overall efficacy, it was noted that there were significant differences in prostate-specific antigen, intra-vesical pressure, detrusor pressure at maximum urine flow rate, abdominal pressure, BOOI, MBOOI, transitional zone volume (TZV), transitional zone index (TZI), IPSS total score, IPSS voiding score, IPSS storage score, Q _max , and post void residual at baseline.

• In binary logistic regression analysis, MBOOI was shown to be the only baseline parameter that showed correlation with the improvements in IPSS, QoL, Q _max , and the overall efficacy.

• By ROC analysis, MBOOI was more optimal compared with BOOI, TZV and TZI in predicting surgical efficacy.