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Mid- to long-term rates of symptomatic adjacent-level disease requiring surgery after cervical total disc replacement compared with anterior cervical discectomy and fusion: A meta-analysis of prospective randomized clinical trials

Journal of Orthopaedic Surgery and Research Oct 15, 2020

Deng Y, Li G, Liu H, et al. - This research was undertaken to correlate mid- to long-term rates of symptomatic adjacent-level disease requiring surgery after cervical disc replacement and anterior cervical fusion. Researchers conducted a meta-analysis and only randomized controlled trials with a follow-up period of more than 48 months reporting rates of symptomatic adjacent-level disease requiring surgery after cervical total disc replacement and anterior cervical discectomy and fusion. The outcomes of this research imply that cervical disc replacement is preferable to anterior cervical fusion in decreasing the incidence of symptomatic adjacent-level disease needing surgery at mid- to long-term follow-up. A review of the literature also indicated that randomized controlled trials evaluating the rate of symptomatic adjacent-level disease needing surgery were insufficient; thus, studies focusing on this individual with longer-term follow-up are needed.

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