Jiang Y, Yu J, Zhang Q, et al. - Researchers determined if the link between hyperuricemia and hypertension is mediated by microalbuminuria. They assessed the temporal links among hyperuricemia, microalbuminuria, and hypertension through cross-lagged panel analysis followed by a causal mediation analysis to verify the temporal consequence. Participants were 1,981 Chinese adults who underwent examinations twice 4 years apart for measurements of blood pressures, urinary albumin to creatinine ratio (UACR), and uric acid. In cross-lagged panel analysis, a significantly smaller link from baseline UACR to follow-up uric acid was revealed, compared with that from baseline uric acid to follow-up UACR. Experts also noted that the links from baseline blood pressures to follow-up UACR were also significantly smaller relative to that from baseline UACR to follow-up blood pressures. According to these findings, microalbuminuria may follow raised uric acid and, in part, mediate its influence on future risk of hypertension among Chinese adults.