Durrani AF, Atta S, Bhat A, et al. - Researchers examined cases of methicillin-resistant Staphylococcal aureus (MRSA) keratitis for the clinical characteristics, management choices, and outcomes. They assessed retrospective interventional case series of 52 culture-proven (52 eyes) cases of MRSA keratitis diagnosed and treated at the University of Pittsburgh Medical Center. The patients had mean age of 66.6±19.2 years with median follow-up time of 147 days. A history of ocular surgery (62.5%), topical corticosteroid use (35.4%), and dry eye syndrome (37.5%) were the most prevalent risk factors. They noted a high burden of systemic disease (95.8%). MRSA causes fulminant keratitis that often require surgical management and has poor visual acuity outcomes. Comparable outcomes were achieved in patients treated with fluoroquinolones in this study vs those treated with fortified vancomycin, however, higher tendency for more severe ulcers at presentation was observed in those treated with fortified vancomycin.