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Methadone and buprenorphine discontinuation among postpartum women with opioid use disorder

American Journal of Obstetrics and Gynecology Apr 15, 2021

Schiff DM, Nielsen TC, Hoeppner BB, et al. - Given that for women with opioid use disorder, the postpartum year is a vulnerable period with greater rates of fatal and non-fatal overdose, researchers sought to examine the discontinuation of methadone and buprenorphine among these women in the year following delivery. In addition, they investigated the extent to which maternal and infant characteristics are linked with time to discontinuation of medications to treat opioid use disorder (MOUD). They used linked administrative data of 211,096 deliveries in Massachusetts between 2011-2014 in this population-based retrospective cohort study investigating MOUD receipt. A total of 2,314 women were identified who received MOUD at delivery. Almost two-thirds of these women remained on MOUD for the full year postpartum. However, there was significant variation in rates by race/ethnicity, degree of prenatal MOUD utilization, and incarceration status. Postpartum treatment receipt may improve by prioritizing treatment continuation across the perinatal continuum, improving gender-specific and family friendly recovery supports, and expanding access to MOUD while incarcerated.

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