Latif A, Ahsan MJ, Mirza MM, et al. - Use of transradial (TR) approach for percutaneous coronary intervention (PCI) in chronic kidney disease (CKD) patients resulted in a lower risk of in-hospital mortality, post-procedural bleeding, and blood transfusion when compared with transfemoral (TF) access.

• PubMed, Embase, Cochrane, ClinicalTrials.gov, and Google Scholar were explored.

• Studies of adults with CKD receiving PCI via a TR vs TF approach were included.

• A random-effects-model using the Mantel‐Haenszel method was employed.

• Eligible were five observational studies with 1,156 and 6,156 patients in the TR and TF arms, respectively.

• Participants had a mean age of 70.5 years, 66% were male and 90% had end-stage renal disease.

• No difference in stroke, myocardial infarction, or fluoroscopy time was observed between TR approach vs TF access.