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Medications that reduce emergency hospital admissions: An overview of systematic reviews and prioritisation of treatments

BMC Medicine Jul 30, 2018

Bobrovitz N, et al. - Using broad search criteria, researchers searched MEDLINE, PubMed, the Cochrane Database of Systematic Reviews & Database of Abstracts of Reviews of Effects, Google Scholar and the websites of ten major funding agencies and health charities to determine which medications affect emergency hospital admissions and to prioritize therapies for quality measurement and improvement. According to the data from this systematic review, 11 medications were identified that could be considered in quality monitoring and improvement strategies to help decrease emergency hospital admission rates. These therapies were for heart failure (angiotensin-converting-enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists and digoxin), stable coronary artery disease (intensive statin therapy), asthma exacerbations (early inhaled corticosteroids in the emergency department and anticholinergics), chronic obstructive pulmonary disease (long-acting muscarinic antagonists and long-acting beta-2 adrenoceptor agonists) and schizophrenia (second-generation antipsychotics and depot/maintenance antipsychotics). These findings should be pertinent to any health system who see a lot of chronic disease and increasing burden of acute services.

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