Goyal N, Tsivgoulis G, Malhotra K, et al. - In this multicenter study coupled with the meta-analysis, researchers evaluated the outcomes of patients with mild-deficits ELVO (mELVO) treated with mechanical thrombectomy (MT) vs best medical management (bMM). During a 5-year period, they retrospectively pooled patients with mELVO from 16 centers. In total, 251 patients with mELVO who were treated with MT were analyzed. Compared with bMM, higher odds of asymptomatic intracerebral hemorrhage with mechanical thrombectomy was documented. Findings indicate comparable MT and bMM results in patients with stroke with mELVO, but no conclusions can be drawn on the impact of therapy. MT was linked to higher odds of symptomatic intracranial hemorrhage in unadjusted analyses in the meta-analysis of four studies. In multivariable analyses, MT was associated with higher odds of asymptomatic ICH. A randomized clinical trial may further resolve clinical equipoise.