Lisonkova S, Razaz N, Sabr Y, et al. - Researchers conducted a retrospective population‐based cohort study of mothers with a singleton hospital live birth or stillbirth at ≥ 24 weeks’ gestation (n = 1,078,323) in order to ascertain the incidence, risk factors and adverse birth outcomes linked with elevated liver enzymes and low platelets (HELLP) syndrome. Using ICD‐10‐CA diagnostic code from delivery hospitalization data, HELLP syndrome was identified in 2.5 per 1,000 singleton deliveries (n = 2,663). Observations revealed correlation of HELLP syndrome with higher maternal death rate, and substantially higher severe maternal and neonatal morbidity, and perinatal mortality. Age ≥ 35 years, rural residence, nulliparity, parity ≥ 4, prepregnancy and gestational hypertension and diabetes, assisted reproduction, chronic cardiac conditions, systemic lupus erythematosus, obesity, chronic hepatic conditions, placental disorders (eg fetomaternal transfusion) and congenital anomalies were identified as the risk factors. An inverse association was observed of PROM and age < 25 years with HELLP syndrome.