Maternal, neonatal insulin resistance and neonatal anthropometrics in pregnancies following bariatric surgery
Metabolism Apr 12, 2019
Maric T, et al. - In this study, researchers examined the effect of bariatric surgery on maternal and neonatal insulin resistance (IR) and composition of neonatal body fat. In 41 post-bariatric and 82 pregnant women with similar early pregnancy body mass index but no history of such surgery, maternal IR at 28 weeks of gestation during 2-hour 75 g oral glucose tolerance test (OGTT), neonatal IR from umbilical cord venous blood, and neonatal birth weight and body fat composition at birth were assessed. According to findings, pregnancy following bariatric surgery was related to reduced maternal IR and altered neonatal body composition with significantly lower birth weight and adiposity—but no cord IR improvement. Despite being lighter and thinner, the offspring of post-bariatric surgery women have similar cord IR vs women's offspring without surgery.
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