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Maternal hepatitis B or hepatitis C virus carrier status and long‐term infectious morbidity of the offspring: A population‐based cohort study

Journal of Viral Hepatitis Apr 15, 2020

Freha NA, et al. - Researches conducted a population‐based cohort study, including all singleton deliveries between the years 1991‐2014 at a tertiary medical center in order to determine the long‐term effects of maternal hepatitis B virus (HBV) or hepatitis C virus (HCV) carrier status on the long‐term infectious morbidity of their offspring. During the study period, they identified 242,905 (99.7%) non‐carrier mothers, 591 (0.2%) HBV carriers and 186 (0.1%) HCV carriers. Offsprings of HBV carriers vs those of HCV carriers and non‐carriers had significantly higher hospitalizations related to infectious morbidity. Findings suggest an independent value of maternal HBV carrier status as risk factor for long‐term infectious morbidity of the offspring, particularly for gastrointestinal and respiratory infections.

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