Wang L, et al. - In infertile patients undergoing their first in vitro fertilization (IVF) treatment, researchers investigated the influence of maternal chronic hepatitis B virus infection on pregnancy outcomes. In this retrospective case-control study, they analyzed 8,550 infertile women, including 180 HBsAg⁺HBeAg⁺, 714 HBsAg⁺HBeAg^-, and 7,656 HBsAg seronegative controls having their first IVF treatments. Observations revealed no independent impact of hepatitis B virus infection on pregnancy outcomes, although, prolonged infertility duration, a high frequency of secondary infertility and ovulatory disorders, and a reduced implantation rate were evident in correlation to the infection.