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Maternal chronic hepatitis B virus infection does not affect pregnancy outcomes in infertile patients receiving first in vitro fertilization treatment

Fertility and Sterility May 20, 2019

Wang L, et al. - In infertile patients undergoing their first in vitro fertilization (IVF) treatment, researchers investigated the influence of maternal chronic hepatitis B virus infection on pregnancy outcomes. In this retrospective case-control study, they analyzed 8,550 infertile women, including 180 HBsAg+HBeAg+, 714 HBsAg+HBeAg-, and 7,656 HBsAg seronegative controls having their first IVF treatments. Observations revealed no independent impact of hepatitis B virus infection on pregnancy outcomes, although, prolonged infertility duration, a high frequency of secondary infertility and ovulatory disorders, and a reduced implantation rate were evident in correlation to the infection.

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