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Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

PLoS Medicine Mar 07, 2019

Voerman E, et al. - Via conducting an individual participant data meta-analysis of data from 162,129 mothers and their children from 37 pregnancy and birth cohort studies from Europe, North America, and Australia, researchers evaluated the separate and combined maternal body mass index (BMI) and gestational weight gain associations with the risk of childhood overweight/obesity and their population impact. According to findings, an increased risk of childhood overweight/obesity was related to higher maternal pregnancy BMI and gestational weight gain, with the strongest effects at later ages. However, in addition to pre-pregnancy BMI, the effect of gestational weight gain was small. Investigators estimated that 21.7% to 41.7% of childhood overweight/obesity prevalence could be attributed to joint maternal overweight and obesity, whereas excessive gestational weight gain could be attributed to 11.4% to 19.2%.
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