Yadav S, Karam D, Riaz IB, et al. - In order to acquire a better understanding of treatment patterns and prognostic factors for male breast cancer (MBC), researchers analyzed 10,873 MBC cases with TNM stage I to stage III diagnosed between 2004 and 2014 in the National Cancer Data Base. They noted that 24% of patients received breast-conserving surgery and radiotherapy was received by 70% of patients undergoing breast conservation. As for the rates of total mastectomy, contralateral prophylactic mastectomy, radiotherapy following breast conservation, ordering of Oncotype DX, and the use of endocrine therapy, a significant rise was reported throughout the study duration. Older age, black race, higher Charlson Comorbidity Index, high tumor grade and stage of disease, and undergoing total mastectomy were identified as factors related to worse overall survival, in multivariate analysis. Factors that showed a link with better overall survival were living in a higher income area; having progesterone receptor–positive tumors; and receipt of chemotherapy, radiotherapy, and endocrine therapy. Although there is a scarcity of prospective randomized trials in patients with MBC, growth in the treatment of this disease has been seen over the years.