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Macular vascular changes in pregnant women with gestational diabetes mellitus by optical coherence tomography angiography

BMC Ophthalmology Apr 14, 2021

Liu G, et al. - Researchers conducted the study for observing the microvasculature changes in eyes of gestational diabetes mellitus (GDM) women compared with normoglycemic pregnant women and non-pregnant women by optical coherence tomography-angiography. GDM women, age-matched normoglycemic pregnant women and non-pregnant women were involved in this investigation. A total of 99 individuals were enrolled in this study from September 2019 to April 2020. Under pregnancy and GDM states, changes in vascular density implied a redistribution of the capillary network from the superficial to the deep layer. Although the transient hyperglycemia exacerbates the changes of capillary “dropout”, the GDM group showed the improvement of central macular thickness thinning and foveal avascular zone enlargement during pregnancy.

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