Sung SY, et al. - Researchers examined patients with pathologically confirmed T1–2N0 non-small-cell lung cancer (NSCLC) to determine the impact of lymphovascular invasion (LVI) on the prognosis and patterns of recurrence in these subjects. They defined and analyzed local recurrence, nodal recurrence, and distant metastasis for patients who underwent complete resection and were diagnosed between March 2000 and January 2012. They found a significant decrease in 5-year disease-free survival among patients with LVI. Furthermore, a significantly increased risk of nodal and distant recurrence was reported in the presence of LVI. Overall, LVI was identified as a negative prognostic factor in patients with stage I–IIA NSCLC.