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Low vitamin D level was associated with metabolic syndrome and high leptin level in subjects with nonalcoholic fatty liver disease: A community-based study

BMC Gastroenterology Jul 21, 2019

Chen LW, et al. - In this community-based study involving 1,922 candidates, researchers explored the relationship between serum vitamin D levels and nonalcoholic fatty liver disease (NAFLD) parameters, like metabolic syndrome (MS), inflammatory cytokines (tumor necrosis factor, high sensitive C-reactive protein) and adipokines (adiponectin, leptin). The level of vitamin D was assessed by quartile divide or used the classification of deficiency (< 20 ng/ml), insufficiency (20–30 ng/ml) and sufficiency (> 30 ng/ml). Investigators found that those with low levels of vitamin D had higher odds of MS vs those with high levels of vitamin D. There was a positive correlation between Vitamin D level and age and male; vitamin D level negatively correlated with serum leptin level.

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