Zaigham S, et al. - Despite a higher prevalence of kidney disease in those with reduced lung function, the longitudinal link between low lung function and future risk of chronic kidney disease (CKD) has not been broadly investigated, therefore, researchers addressed this topic in this study with 20,700 men and 7,325 women. The evaluation of baseline lung function was performed in these participants from 1974 to 1992. Gender-specific quartiles of forced expiratory volume in 1 s (FEV₁) and forced vital capacity (FVC) (L) were defined (Q4: highest, reference) and the cohort was also categorized by the FEV₁/FVC ratio (≥ or < 0.70). A 41 years of follow-up revealed 710 and 165 incident CKD events (main diagnosis) in males and females respectively. Findings revealed low FEV₁ and FVC levels at baseline as a risk factor for the occurrence of future incident CKD in males. Those carrying an increased risk of future CKD could be identified via kidney function monitoring in those exhibiting decreased vital capacity in early life.