Bönstrup M, Krawinkel L, Schulz R, et al. - Given a pivotal role of movement preparatory low-frequency oscillations (LFOs) in cortical control of movement, and recent animal data hinting a mechanistic role of motor cortical LFOs in stroke motor deficits and showing neuromodulation intervention with therapeutic benefit, researchers performed this study to determine the relevance of these in the human stroke pathophysiology. Among 33 patients with motor stroke and 19 healthy volunteers, included in a longitudinal cohort study, they examined the link between movement-preparatory LFOs during the performance of a visuomotor grip task and motor function. In this study, the first human evidence for the association between movement-preparatory LFOs and functional recovery post-stroke was generated, expanding their relevance for movement control. Exploration of targeted, LFOs-restorative brain stimulation therapy in human stroke patients may be an interesting step as suggested by these findings.