Kagaya Y, et al. - Researchers investigated the feasibility and the impacts of cardiac shockwave (SW) therapy on left ventricular (LV) remodeling after acute myocardial infarction (AMI) in humans who successfully underwent primary percutaneous coronary intervention (PCI) (peak-creatine kinase<4000 U/l). Using propensity score matching, a comparison was performed between these patients and historical AMI controls. No procedure-related complications or adverse effects were reported. Findings demonstrated the feasibility of low-energy extracorporeal cardiac SW therapy. Moreover, this therapy, when used as an adjunctive to primary PCI, could ameliorate postmyocardial infarction LV remodeling in patients with acute myocardial infarction.