Gemine RE, et al. - In this largest prospective study, researchers determined the prevalence of smoking in 1,124 patients with newly diagnosed non-small cell lung cancer (NSCLC) between 2010-2016, and also investigated if smoking status at baseline and cessation were independently related to 1-year survival. The study was conducted at 28 sites and was based in secondary and primary care. This investigation validated smoking in NSCLC. According to findings, smoking was prevalent at the time of diagnosis among a third of people. Compared with never-smokers and former smokers, lower 12-month survival was evident among smokers. A 25% attenuation in mortality was noted in relation to smoking cessation, which was not statistically significant but, possibly, clinically important once other factors were adjusted.