Trief PM, et al. - In adults with type 1 diabetes, researchers measured longitudinal change in depression symptoms over ≥4 years and between if there was a relationship between depression symptom status and glycemia. Depression status was defined as Persistent Elevated Depression Symptoms (EDS) that categorizes patients into the following categories- Resolved EDS, New Onset EDS and Not Depressed. Out of 2,744 participants, 131 (5%) had Persistent EDS, 122 (4%) had Resolved EDS, 168 (6%) had New Onset EDS, and 2,323 (85%) were Not Depressed. An association between an increase in PHQ-8 and an increase in HbA_1c was noticed. Diabetic ketoacidosis (DKA) was more likely in patients with New Onset EDS and Persistent EDS. A clear relationship was seen between depressive symptoms, the occurrence of severe hypoglycemia, and DKA, suggesting successful treatment of depression symptoms can lead to better long-term diabetes results.