Long-term urological and gynecological outcomes following complete primary repair in females with bladder exstrophy
Journal of Pediatric Urology Jul 31, 2021
Canalichio K, Ahn J, Hwang C, et al. - Because long-term continence outcomes in patients undergoing complete primary repair of exstrophy (CPRE) have shown that a subset of patients do not achieve continence until after puberty, researchers conducted this retrospective review to update the continence outcomes and describe gynecological outcomes for females who underwent CPRE. Inclusion criteria were females with classic bladder exstrophy who underwent CPRE, whereas exclusion criteria were variant diagnoses and age < 4 years. Only 18 patients matched the requirements for inclusion. Overall, the majority of women who had CPRE achieved complete or partial continence, though most needed additional procedures and time to do so. Furthermore, volitional voiding was possible. Patients who required clean intermittent catheterization had significantly lower bladder capacity. Following menarche, the majority of women required medical or surgical intervention for gynecologic concerns. This study emphasizes the unique needs of girls and young women with bladder exstrophy, as well as the importance of close long-term urologic and gynecologic management throughout development.
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