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Long-term status of predicted body fat percentage, body mass index, and other anthropometric factors with risk of colorectal carcinoma: Two large prospective cohort studies in the U.S.

International Journal of Cancer Jul 10, 2019

Akiko Hanyuda A, et al. - Researchers sought to examine the differential associations between predicted body fat percentage and body mass index (BMI) with the risk of colorectal carcinoma (CRC) (n=2,017) using a Cox proportional hazards regression model. In addition, they determined the associations between CRC incidence and different adiposity measurements. Predicted body fat percentage and BMI had a similar increased risk of CRC risk. Compared to BMI, predicted fat mass and waist circumference were slightly more strongly associated with CRC risk. This study thereby provides further evidence that a greater amount of body fat might contribute to CRC risk in both sexes. They estimated the susceptibilities of specific body composition with CRC risk in an inexpensive and minimally invasive manner using the innovative approach. Furthermore, for predicting cancer risk in a relatively healthy population, the typically used measures of BMI and waist circumference are robust measures of adiposity.
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