Jacob L, et al. - In a large cohort of almost 20,000 transient ischaemic attack (TIA) patients followed in general practices in Germany, researchers examined the long-term risk of stroke and associated predictors. Study participants included 19,824 patients with an initial TIA diagnosis and subsequently followed up in one of 1,262 general practices in Germany between January 2007 and December 2016. Data reported that 18.3% of people were diagnosed with stroke within 10 years of the initial TIA diagnosis. Findings suggested a positive association of age with stroke, with hazard ratios ranging from 1.88 in individuals aged 51–60 years to 4.00 in those aged > 80 years. In addition, the risk of stroke was further impacted by male sex, hypertension, diabetes mellitus, atrial fibrillation and ischaemic heart disease. Eventually, as protective factors new oral anticoagulants, heparins, diuretics, angiotensin II receptor blockers, and platelet aggregation inhibitors have been identified.