Walter N, Kerschbaum M, Pfeifer C, et al. - The present study was conducted to assess the long-term impact of aseptic long bone non-union on the patients’ physical health state and psychological wellbeing. For this purpose, researchers evaluated the quality of life after successful surgical treatment of long bone non-union. Between November 2009 and March 2019, 61 individuals with aseptic long bone non-union surgically treated in our department with achieved bone consolidation were enrolled. Quality of life was evaluated with the EQ-5D and SF-36 outcome instruments as well as with an ICD-10 based symptom rating and compared to normative data. Patients still report significantly lower quality of life in comparison to normative data even 4.7 years on average after surgically successful treatment of aseptic long bone non-union. Further clinical trials on non-unions should focus on patient-related outcome measures. It has been considered that newly emerging treatment strategies and interdisciplinary approaches should be implemented to improve the overall quality of life of non-union patients.