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Long-term outcomes of an extracorporeal irradiated autograft for limb salvage operations in musculoskeletal tumours: Over ten years’ observation

The Bone & Joint Journal Sep 10, 2019

Oike N, Kawashima H, Ogose A, et al. - In this retrospective study, researchers examined the long-term results of patients observed over 10 years after resection en bloc and reconstruction with extracorporeal irradiated autografts. The study sample consisted of 27 patients [mean age was 31.7 years (9 to 59)] who had resection en bloc and reimplantation of an extracorporeal irradiated autograft. The irradiated autograft did not recur and the autograft survived in 24 patients. Nonunion, subchondral bone collapse and deep infection were major complications included. Data reported that the mean Musculoskeletal Tumor Society score at the last follow-up was 84.3%. Extracorporeal irradiated autograft is an effective method of reconstruction for malignant musculoskeletal tumours, taking into account long-term outcomes.
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