Mumford J, et al. - Researchers for the first time assessed the natural history of bone health in patients with a previous diagnosis of adolescent-onset anorexia nervosa (AN) at 5 or 10 years post-diagnosis. At 5 years (T5, n = 28) or 10 years (T10, n = 13) after their first admission to hospital related to AN, 41 women with a history of adolescent-onset AN attended a follow-up bone health assessment. They included dual-energy x-ray absorptiometry measurements of the total body, lumbar spine, and proximal femur, peripheral quantitative computed tomography at the radius and tibia, anthropometric measurements, serum biochemistry, fracture history, and a patient questionnaire. According to findings, dual-energy x-ray absorptiometry body composition showed a recovery of fat mass and lean tissue mass. Although not to a degree that required clinical intervention, AN patients showed a statistically significant reduction in radiographic bone health measures during follow-up. Overall, investigators confirmed persistent effects of AN on bone health.