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Long-term outcomes after kidney transplant failure and variables related to risk of death and probability of retransplant: Results from a single-center cohort study in Brazil

PLoS Neglected Tropical Diseases Jan 27, 2021

Requião-Moura LR, Albino CRM, Bicalho PR, et al. - Researchers assessed death or retransplantation post-graft loss (GL) among 115 transplant patients with kidney allograft failure who were observed for 44.1 (21.4; 72.6) months following GL, in this historical single-center cohort study in Brazil. The 5-year likelihood of retransplantation and death was estimated to be 38.7% and 37.7%, respectively. A higher probability of retransplantation was noted in patients who resumed dialysis with higher concentrations of hemoglobin and was shown to be lower in blood type O patients, which was related to a lower frequency of retransplantation with a subsequent living-donor kidney. Findings showed that 5-year likelihood of retransplantation was not less compared with that of death. Hemoglobin concentration prior to resuming dialysis and ABO blood type were identified as the variables associated with the likelihood of retransplantation, while death risk was found to be related to comorbidities and residual eGFR.

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