Tian YM, et al. - Investigators recruited 865 nasopharyngeal carcinoma patients from 2001 to 2008 to examine the long-term outcome and pattern of failure following intensity-modulated radiotherapy (IMRT). They observed 92.0%, 83.4%, and 78.6% as the respective 10-year local recurrence-free survival, distant metastasis-free survival, and disease-specific survival (DSS). They recorded the death of 209 patients, including 59% of deaths from distant metastasis. As compared to participants with high-risk stage III disease who received IMRT alone, the 10-year DSS was higher in subjects who received chemoradiotherapy. No survival difference was reported for subjects with stage II and low-risk stage III disease.