Ramgren JJ, Nozohoor S, Zindovic I, et al. - Via evaluating data after repair for complete atrioventricular septal defect over a 25-year period, researchers sought to assess survival and determine risk factors for left atrioventricular valve–related reoperations. From April 1993 to October 2018, they identified a total of 304 consecutive patients who underwent surgical correction for complete atrioventricular septal defect. Overall, 30-day mortality of 1.0% (3/304) was noted with no difference between young and older infants. At 20-year follow-up, the total population had overall survival of 95.1%. Poor survival was observed in independent correlation with following risk factors: presence of an additional ventricular septal defect, previous coarctation of the aorta, persistent left superior vena cava, and genetic syndromes other than Trisomy 21. Data suggest that early repair for complete atrioventricular septal defect could lead to achievement of excellent long-term survival; there was a low necessity for reoperations due to left atrioventricular valve regurgitation. Primary correction in patients aged less than 3 months is, when clinically essential, well tolerated. In the majority of patients, palliative procedures can be avoided.