Friedenreich CM, Wang Q, Yasui Y, et al. - Researchers investigated the influence of the amount of exercise prescribed in a year-long exercise intervention on breast cancer biomarker levels (C-reactive protein, insulin, glucose, HOMA-IR, estrone, sex hormone binding globulin, total estradiol, and free estradiol) 1 year later. A 24-month follow-up study (2012–2014) to the Breast Cancer and Exercise Trial in Alberta (BETA; a 12-month, two-armed (1:1), two-center randomized controlled trial of exercise in 400 cancer-free, postmenopausal women) was performed. Patients were asked to perform moderate–vigorous aerobic exercise, 5 days/week (3 days/week supervised) for 30 minutes/session (MODERATE) or 60 minutes/session (HIGH). Outcomes revealed no effects on longer-term biomarkers when the aerobic exercise was prescribed for 300 vs 150 minutes/week for 12 months to inactive, postmenopausal women.