Long-term effect of intraocular lens vs contact lens correction on visual acuity after cataract surgery during infancy: A randomized clinical trial
JAMA Ophthalmology Mar 01, 2020
Lambert SR, Cotsonis G, DuBois L, et al. - In this randomized clinical trial involving 114 patients, researchers contrasted long-term visual outcomes with contact lens vs intraocular lens (IOL) correction following unilateral cataract surgery during infancy. Participants in the study were infants with a unilateral congenital cataract who had cataract surgery with or without primary IOL implantation between 1 and 6 months of age. Best-corrected visual acuity was measured at age 10.5 years for 110 (58 girls and 52 boys) of the 114 patients registered as infants. The estimate was imprecise although the overall difference in median visual acuity between the 2 groups was small. As in previous phases of the study, visual acuity findings were highly variable with only 27 children with their treated eye achieving excellent visual acuity and 50 children with poor vision in the treated eye. Implanting an IOL at the time of cataract extraction was neither helpful nor harmful to the visual outcome.
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