Choe G, Ghanie A, Riely G, et al. - Long-term outcomes in patients with thymic malignancies metastatic to the pleura or pericardium were characterized via retrospectively evaluating 72 patients (median age 51 [range 25-80]) who underwent resection for de novo thymic malignancies metastatic to the pleura between May 1997 and December 2017. Fifty-seven patients (79%) were diagnosed with thymoma and 15 (21%) with thymic carcinoma. Chemotherapy, radiation, or both were recieved by the majority of the patients (67/72; 93%). Thymectomy with pleurectomy was performed in 48 patients, extrapleural pneumonectomy was done on 7 patients, thymectomy alone was undertaken in 10 patients, and there were 7 patients who were unresectable. Overall survivals of 73%, 51%, and 18% at 5-, 10-, and 15-year, respectively, and median overall survival of 11 years (median follow-up, 5.9 years) were evident. The patients commonly experienced repeat episodes of progression and treatment (median, 3 episodes/patient). As per findings, treatment can lead to the achievement of prolonged survival and, in some cases, cure among patients with thymic malignancies metastatic to the pleura or pericardium. For select patients, researchers suggest aggressive multimodality therapy as appropriate.