Gasperetti A, Schiavone M, Ziacchi M, et al. - Researchers investigated a large real-world multicenter subcutaneous implantable cardioverter-defibrillator (S-ICD) cohort for assessing device-related complications over time. Using a 19-institution European registry, patients implanted with an S-ICD from January 2015 to June 2020 were enrolled. Of 1254 patients (median age 52.0) enrolled, 117 (9.3%) developed complications for a total of 127 device-related complications (23.6% managed conservatively and 76.4% needed reintervention), as revealed by a follow-up of 23.2 months. This follow-up period revealed an overall complication rate of 9.3%. Findings revealed that 2.2% of patients experienced early unanticipated device battery depletions, while 0.3% suffered lead fracture, which is in line with the expected rates reported by Boston Scientific.