Bancks MP, et al. - In order to estimate the long-term absolute risk of cardiovascular disease (CVD) (defined as fatal/nonfatal coronary heart disease and fatal/nonfatal stroke) based on fasting glucose (FG) levels lower than the diabetes threshold, researchers collected data from seven observational cohorts of US black and white men and women followed from 1960 to 2015. The study sample consisted of 19,630 people without a prior CVD event. Findings revealed that CVD risk ranged from 15.3% (<5.0 mmol/L) to 38.6% (diabetes levels) among women over 85 years of age and, among men, from 21.5% (5.0–5.5 mmol/L) to 47.7% (diabetes levels). An FG of 6.3–6.9 mmol/L was linked to a higher long-term risk of CVD vs the lowest FG in men, but not women. Data suggested a high long-term absolute risk for CVD persisted in middle-aged people with diabetes. For midlife CVD prevention, the importance of blood glucose monitoring was strongly supported in this analysis.