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Long and short interpregnancy intervals increase severe maternal morbidity

American Journal of Obstetrics and Gynecology Jun 11, 2021

Garg B, Darney B, Pilliod RA, et al. - Researchers investigated whether interpregnancy interval (stratified as < 6, 6–11, 12–17, 18–23, 24–59, and ≥ 60 months) correlates with severe maternal morbidity, which is considered both with and without blood transfusion. In this retrospective cohort study, 1,669,912 women met the inclusion criteria. Among these women, 14,529 (0.87%) had severe maternal morbidity and 4,712 (0.28%) had nontransfusion severe maternal morbidity. Women with short interpregnancy interval (< 6 months) and long interpregnancy interval (≥ 60 months) were noted to be at higher risk of severe maternal morbidity relative to women with normal interpregnancy interval (18–23 months). Women with long interpregnancy interval (≥ 60 months) were at significantly higher risk of nontransfusion severe maternal morbidity. These findings suggest interpregnancy interval to be a modifiable risk factor, and emphasize counseling women to have an adequate gap between pregnancies as it may be an important strategy to lower the risk of severe maternal morbidity.

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