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Long‐term quality of life & functional outcomes after treatment of oropharyngeal cancer

Cancer Medicine Dec 16, 2020

Scott SI, Rubek N, Charabi BW, et al. - Researchers examined a cohort of patients treated for oropharyngeal squamous cell carcinoma (OPSCC), to longitudinally compare functional and quality of life (QoL) outcomes between patients who underwent primary transoral robotic surgery (TORS) vs those managed with radiotherapy (RT). This analysis involved 44 patients treated with primary TORS (n = 31) or RT (n = 13) for any stage OPSCC. At 12‐month follow‐up, a significant drop in salivary flow rates was evident in the RT group, with the biggest reductions in QoL subscale scores documented in the RT group for dry mouth and sticky saliva. At 1 year, shoulder impairment was rare in both groups. Overall good functional as well as QoL outcomes were noted at 1 year post-treatment, in a comprehensive analysis of this cohort managed for OPSCC. However, in terms of swallowing function, there was persistent impairment in both groups. The QoL questionnaires exhibited worse scores in only one subscale (sticky saliva), at 12‐months follow‐up, in the TORS group.

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