Long‐term follow‐up of a racially and ethnically diverse population of men with localized prostate cancer who did not undergo initial active treatment
Cancer Medicine Sep 27, 2020
Slezak JM, Van Den Eeden SK, Cannavale KL, et al. - The present study was conducted to evaluate long‐term follow‐up of a racially and ethnically diverse population of men with localized prostate cancer who did not undergo initial active treatment. Researchers distinguished men diagnosed with localized, Gleason ≤ 7 prostate cancer who were not treated within 1 year of diagnosis from 1997–2007. They applied Cox model of all‐cause mortality and Fine‐Gray sub distribution model to account for competing risks to investigate for racial/ethnic variations in outcomes adjusted for clinical factors. This study included a total of 3,925 men, 749 Hispanic, 2,415 non‐Hispanic white, 559 non‐Hispanic African American, and 202 non‐Hispanic Asian/Pacific Islander. This study's findings demonstrate that significant risks of metastasis and prostate cancer mortality exist in untreated men beyond 10 years after diagnosis, but are not equally distributed among racial/ethnic groups.
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