Lee K, Ahn JM, Yoon YH, et al. - Researchers sought to determine long‐term outcomes after percutaneous coronary intervention vs coronary artery bypass grafting (CABG) for left main coronary artery disease with or without diabetes mellitus (DM). From the MAIN‐COMPARE (Revascularization for Unprotected Left Main Coronary Artery Stenosis: Comparison of Percutaneous Coronary Angioplasty vs Surgical Revascularization) registry, they used the 10‐year data from 2,240 patients with left main coronary artery revascularization; of these, 722 (32%) had DM. The outcomes assessed were all‐cause mortality; a composite of death, Q‐wave myocardial infarction, or stroke; and target‐vessel revascularization. Percutaneous coronary intervention and CABG did not differ in the adjusted 10‐year risks of death and composite outcome in the overall population; this was observed irrespective of DM status. In this cohort of patients with longest follow‐up who underwent left main coronary artery revascularization, diminishing of the clinical impact of DM favoring CABG over percutaneous coronary intervention was observed over time from the bare‐metal stent to the drug‐eluting stent era.