• Profile
Close

Location of glomerular immune deposits, not codeposition of immunoglobulin G, influences definitive renal outcomes in immunoglobulin A nephropathy

Nephrology Dialysis Transplantation Jul 05, 2018

Alvarado AS, et al. - Researchers investigated how codeposition of IgG in the glomeruli or the presence of immune deposits in the glomerular capillary walls influence clinical outcome in immunoglobulin (IgA) nephropathy (IgAN). They examined a multicenter IgAN cohort, with 80 IgAN biopsies. These biopsies were retrospectively divided into groups, the association of which with the composite primary outcome of renal replacement therapy, renal transplant, death or doubling of serum creatinine (SCr) concentration was assessed. Findings revealed the association of both IgG co-deposition and the location of glomerular immune deposits in the peripheral capillary walls with greater histologic activity on renal biopsy. A significantly increased risk for end-stage renal disease, transplant, death and/or doubling of SCr was reported in relation to only the location of glomerular immune deposits in the peripheral capillary walls.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay