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Live birth and multiple birth rates in US in vitro fertilization treatment using donor oocytes: A comparison of single-embryo transfer and double-embryo transfer

Journal of Assisted Reproduction and Genetics Jun 25, 2018

Klenov VE, et al. - Live birth rates (LBRs) and multiple birth rates (MBRs) were compared between elective single-embryo transfer (eSET) and double-embryo transfer (DET) in donor oocyte in vitro fertilization (IVF) treatments in both a cycle-level and clinic-level analysis. Researchers analyzed donor oocyte IVF treatments performed by US IVF clinics reporting to the Centers for Disease Control and Prevention in 2013–2014. Compared to clinics with lower-frequency eSET utilization, US IVF clinics utilizing eSET with higher frequencies showed clinically comparable LBRs and significantly lower MBRs. With higher eSET utilization, they noted increase in mean offspring birth weight and gestational age at delivery.
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