Jin JL, et al. - Researchers assessed if elevated lipoprotein(a) has any effect on cardiovascular events (CVEs) in patients with different glucose metabolism status and stable coronary artery disease (CAD). In this multicenter study involving 5,143 patients, 435 CVEs occurred over a median of 6.1 years’ follow-up. There was no significant difference between normal glucose regulation and pre-diabetes mellitus groups in the occurrence of CVEs. When glucose metabolism status was combined with stratifying factors, 30 ≤ Lp(a) < 50 mg/dL and Lp(a) ≥50 mg/dL were linked with a significantly inceased risk of subsequent CVEs in pre-DM. For the first time, outcomes showed that elevated levels of Lp(a) could affect the prognosis in patients with stable CAD pre-DM, suggesting that in stable CAD patients with mild impaired glucose metabolism, Lp(a) may further stratify.