Takahara M, Watanabe H, Shiraiwa T, et al. - This study was attempted to assess lifestyle changes and their impact on glycemic control and weight control in patients with diabetes during the coronavirus disease 2019 (COVID-19) pandemic in Japan. Between 28 March and 30 May 2020, researchers retrospectively examined 1,402 outpatients with diabetes at a clinic in Osaka, Japan, who responded to an interview sheet regarding lifestyle changes during the COVID-19 pandemic. The linear regression model was used to investigate the relationship of lifestyle changes with hemoglobin A1c (HbA1c) and weight changes from February to May 2020. The cumulative link model was used to evaluate the relationship with a clinically important change of HbA1c (by ≥ 0.3%) and body weight (by ≥ 3%). During the COVID-19 pandemic, a considerable number of outpatients with diabetes experienced lifestyle changes. It has been reported that lifestyle changes were correlated with HbA1c and weight changes.