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Lifelong occupational exposure to wood dust and risk of nasal and nasopharyngeal cancer

International Journal of Cancer Sep 02, 2017

Siew SS et al. - In the current study it was shown that lifelong cumulative exposure (CE) to softwood-dominated mixed wood dusts is associated with an increased risk of nasal adenocarcinoma.

Methods
A population-based case-control study was conducted on all males with nasal adenocarcinoma (n=393 ), other types of nasal cancer (n=2446), and nasopharyngeal cancer (n=1747) diagnosed in 4 Nordic countries.
CEs to wood dust and formaldehyde before the index date were quantified. 

Results
The risk of nasal adenocarcinoma following wood dust exposure was increased.
The HR in the highest CE category of wood dust (greater than or equal to 28.82 mg/m3-years) was 16.5.
Neither non-adenocarcinoma of the nose nor nasopharyngeal cancer was associated with wood dust exposure. 
 

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