Wolters FJ, et al. - Researchers conducted this investigation to analyze life expectancy with and without dementia by creating multi-state lifetables, and evaluated the impact of postponing disease onset. From 1990 to 2015, 10,348 people from the population-based Rotterdam Study were followed for dementia and death. The investigators observed that overall life-expectancy of women ranged from 18.0 years at age 65 to 2.3 years at age 95, whereas overall life-expectancy of men ranged from 15.6 years at age 65 to 1.8 years at age 95—of which 3.7% and 35.3% was lived with dementia, respectively. Data showed that postponing dementia onset by 1-3 years resulted in a 25% to 57% decline in years lived with dementia. Findings revealed that survival after dementia diagnosis ranged from 6.7 years, when diagnosed before age 70, to 2.6 years (2.3-2.9) > 90 years. In terms of healthy life-years lost, dementia places a large burden on people and society; however, this, the authors indicated, is potentially highly amendable by preventive interventions at the population level.